Creatine Ethyl-Ester Unstable, Say Researchers

New research shows that creatine ethyl-ester - a new but unproven version of the popular sports supplement creatine – does not work as well as regular creatine.

One of the most effective supplements for anyone who wants to boost their gym performance, creatine monohydrate is used regularly by athletes, bodybuilders and regular gym-goers. But while many companies have released different versions of creatine, which are supposed to work better than the standard product, very few of these new supplements have been studied in properly controlled clinical trials.

This latest research, conducted by a team of British scientists and presented at the 4th International Society of Sports Nutrition (ISSN) annual meeting in Las Vegas, is one of the first studies to put creatine ethyl-ester to the test.

Researchers Dr. Robert Child and Dr. Mark J Tallon compared two products containing creatine ethyl-ester with creatine monohydrate. Despite advertising claims to the contrary, Child and Tallon found that creatine ethyl-ester was actually less stable than regular creatine.

"We found that the addition of the ethyl group to creatine actually reduces acid stability and accelerates its breakdown to creatinine," says Tallon. "This substantially reduces creatine availability in its esterified form, which makes creatine ethyl-ester inferior to creatine monohydrate as a source of creatine."

"To date, no published study has shown that creatine ethyl-ester works any better than regular creatine," adds study co-author Dr. Robert Child. "In fact, our work shows that it’s less stable. Anyone should think twice about spending their money on this type of product."

Source
Child, R. & Tallon, M.J. (2007). Creatine ethyl ester rapidly degrades to creatinine in stomach acid. International Society of Sports Nutrition 4th Annual Meeting

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